Krzysztof Wegrzyn was born in Gdansk/Poland. He began playing the violin at an early age, studying with Zenon Brzewski and Irena Dubiska in Warsaw, Wolfgang Marschner in Freiburg and Yfrah Neaman in London. He was a laureate in renowned international competitions (Spohr, Montreal) and won the Szymanowski and Lipizer Competitions.

His concert activities have taken him around the world and he has made numerous recordings for radio, television and CD. His broad repertoire also features works by Lutoslawski, Ligeti, Nono, Schnittke, Pärt and Penderecki. He served as concertmaster of the Hanover State Opera and Philharmonic Orchestra for many years and since 1993 has been a professor at the University of Music and Drama Hanover. Many of his students have won international competitions and play in leading orchestras in Germany.

He has given frequent masterclasses worldwide including at Scuola di Musica di Fiesole, Juilliard School, Aspen and Bowdoin Festivals, Keshet Eilon, Holland Music Sessions, Seoul, Shanghai and Tokyo. He has been a juror at such esteemed violin and chamber music competitions as the Tchaikovski/Moscow, Kreisler/Vienna, Paganini/Genova, ARD/Munich, among others. Furthermore, he is very active in chamber music, for example as the co-founder of the New Warsaw Piano Quintet. Since 1995 he has also served as artistic director of the Gdansk Spring Music Festival in Poland.

Krzysztof Wegrzyn is the founder and Artistic Director of the Hannover International Violin Competition dedicated to Joseph Joachim.

He was awarded the State Music Prize of Lower Saxony in 2004.

He plays a venezian violin of Domenico Montagnana.